Brønsted Acid Catalysis

Due to the vast number of reactions that can be catalyzed by Brønsted acids, a core area of our research focuses on the development and application of chiral organic Brønsted acids for asymmetric counteranion-directed catalysis (ACDC). To date, out efforts in this field have yielded a variety of chiral Brønsted acids, whose potential was demonstrated in a large number of asymmetric transformations. Current explorations aim towards the expansion and generalization of available substrate classes by the rational development of confined and even more active yet highly selective catalyst motifs.