Publications of M. T. Reetz

Kille, S.; Zilly, F. E.; Acevedo, J. P.; Reetz, M. T. Regio- and Stereoselectivity of P450-Catalysed Hydroxylation of Steroids Controlled by Laboratory Evolution. Nature Chemistry 2011, 3, 738–743.

Prasad, S.; Bocola, M.; Reetz, M. T. Revisiting the Lipase from Pseudomonas Aeruginosa: Directed Evolution of Substrate Acceptance and Enantioselectivity Using Iterative Saturation Mutagenesis. ChemPhysChem 2011, 12, 1550–1557.

Reetz, M. T. Laboratory Evolution of Stereoselective Enzymes: A Prolific Source of Catalysts for Asymmetric Reactions. Angewandte Chemie-International Edition 2011, 50, 138–174.

Reetz, M. T. Gerichtete Evolution Stereoselektiver Enzyme: Eine Ergiebige Katalysator-Quelle f r Asymmetrische Reaktionen. Angewandte Chemie 2011, 123, 144–182.

Reetz, M. T.; Krebs, G. P. L. Challenges in the Directed Evolution of Stereoselective Enzymes for Use in Organic Chemistry. Comptes Rendus Chimie 2011, 14, 811–818.

Reetz, M. T.; Zheng, H. B. Manipulating the Expression Rate and Enantioselectivity of an Epoxide Hydrolase by Using Directed Evolution. ChemBioChem 2011, 12, 1529–1535.

Zilly, F. E.; Acevedo, J. P.; Augustyniak, W.; Deege, A.; Häusig, U. W.; Reetz, M. T. Tuning a P450 Enzyme for Methane Oxidation. Angewandte Chemie-International Edition 2011, 50, 2720–2724.

Zilly, F. E.; Acevedo, J. P.; Augustyniak, W.; Deege, A.; Häusig, U. W.; Reetz, M. T. Tuning a P450 Enzyme for Methane Oxidation. Angewandte Chemie 2011, 123, 2772–2776.

Reetz, M. T. Enzym-Design mit Fernwirkung. Neuer Weg zur Optimierung von Enzymen für Industrielle Anwendungen. GIT Labor-Fachzeitschrift 2010, 54, 190–192.

Gavrilov, K. N.; Safronov, A. S.; Rastorguev, E. A.; Groshkin, N. N.; Zheglov, S. V.; Shiryaev, A. A.; Maksimova, M. G.; Petrovskii, P. V.; Davankov, V. A.; Reetz, M. T. Phosphorodiamidite Derivatives of 1,1 '-Bi-2-Naphthol Containing Stereogenic Phosphorus Atoms as Ligands in Enantioselective Catalysis. Russian Chemical Bulletin 2010, 59, 434–440.

Fernández, L.; Jiao, N.; Soni, P.; Gumulya, Y.; De Oliveira, L. G.; Reetz, M. T. An Efficient Method for Mutant Library Creation in Pichia Pastoris Useful in Directed Evolution. Biocatalysis and Biotransformation 2010, 28, 122–129.

Gavrilov, K. N.; Safronov, A. S.; Rastorguev, E. A.; Groshkin, N. N.; Zheglov, S. V.; Shiryaev, A. A.; Maksimova, M. G.; Petrovskii, P. V.; Davankov, V. A.; Reetz, M. T. Phosphorodiamidite Derivatives of 1,1'-Bi-2-Naphthol Containing Stereogenic Phosphorus Atoms as Ligands in Enantioselective Catalysis. Russian Chemical Bulletin 2010, 59, 434–440.

Gavrilov, K. N.; Zheglov, S. V.; Rastorguev, E. A.; Groshkin, N. N.; Maksimova, M. G.; Benetsky, E. B.; Davankov, V. A.; Reetz, M. T. Asymmetric Catalytic Reactions Using P*-Mono-, P*,N- and P*,P*-Bidentate Diamidophosphites with BINOL Backbones and 1,3,2-Diazaphospholidine Moieties: Differences in the Enantioselectivity. Advanced Synthesis & Catalysis 2010, 352, 2599–2610.

Opperman, D. J.; Reetz, M. T. Towards Practical Baeyer–Villiger-Monooxygenases: Design of Cyclohexanone Monooxygenase Mutants with Enhanced Oxidative Stability. ChemBioChem 2010, 11, 2589–2596.

Podtetenieff, J.; Taglieber, A.; Bill, E.; Reijerse, E. J.; Reetz, M. T. An Artificial Metalloenzyme: Creation of a Designed Copper Binding Site in a Thermostable Protein. Angewandte Chemie, International Edition 2010, 49, 5151–5155.

Podtetenieff, J.; Taglieber, A.; Bill, E.; Reijerse, E. J.; Reetz, M. T. An Artificial Metalloenzyme: Creation of a Designed Copper Binding Site in a Thermostable Protein. Angewandte Chemie 2010, 122, 5277–5281.

Reetz, M. T.; Prasad, S.; Carballeira, J. D.; Gumulya, Y.; Bocola, M. Iterative Saturation Mutagenesis Accelerates Laboratory Evolution of Enzyme Stereoselectivity: Rigorous Comparison with Traditional Methods. Journal of the American Chemical Society 2010, 132, 9144–9152.

Reetz, M. T.; Soni, P.; Fernández, L.; Gumulya, Y.; Carballeira, J. D. Increasing the Stability of an Enzyme Toward Hostile Organic Solvents by Directed Evolution Based on Iterative Saturation Mutagenesis Using the B-FIT Method. Chemical Communications (Cambridge) 2010, 46, 8657–8658.

Reetz, M. T.; Wu, S.; Zheng, H.; Prasad, S. Directed Evolution of Enantioselective Enzymes: An Unceasing Catalyst Source for Organic Chemistry. Pure and Applied Chemistry 2010, 82, 1575–1584.

Wu, S.; Acevedo, J. P.; Reetz, M. T. Induced Allostery in the Directed Evolution of an Enantioselective Baeyer-Villiger Monooxygenase. Proceedings of the National Academy of Sciences of the United States of America 2010, 107, 2775–2780.