Publications of Richard Goddard

Sun, Q.; Belting, J.-N.; Hauda, J.; Tymann, D.; Antoni, P. W.; Goddard, R.; Hansmann, M. M. Spiro-C(Sp³)-Atom Transfer: Creating Rigid Three-Dimensional Structures with Ph₂SCN₂. Science 2025, 387, 885–892.

Goddard, R.; Seidel, R. W.; Patzer, M.; Nöthling, N. Crystal Structure of the Biocide Methylisothiazolinone. Crystals 2024, 14, 1100.

Lang, M.; Goddard, R.; Patzer, M.; Ganapathy, U. S.; Dick, T.; Richter, A.; Seidel, R. W. Polymorphism of an Nα-Aroyl-N-Aryl-Phenylalanine Amide: An X-Ray and Electron Diffraction Study. Molbank 2024, 2024, M1851.

Palme, P. R.; Goddard, R.; Richter, A.; Imming, P.; Seidel, R. W. 3-[(Benzo-1,3-Dioxol-5-Yl)Amino]-4-Meth­­Oxy­Cyclo­but-3-Ene-1,2-Dione: Polymorphism and Twinning of a Precursor to an Anti­Mycobacterial Squaramide. Acta Crystallographica, Section C: Structural Chemistry 2024, 80, 375–382.

Seidel, R. W.; Goddard, R.; Kolev, T. M. The Pseudo Symmetric Crystal Structure of 1,4-Diazabicyclo[2·2·2]Octane-1,4-Diium bis(5-Hydroxy-2,4-Dinitrophenolate). Journal of Chemical Crystallography 2024, 54, 125–131.

Seidel, R. W.; Goddard, R.; Lang, M.; Richter, A. Nα-Aroyl-N-Aryl-Phenylalanine Amides: A Promising Class of Antimycobacterial Agents Targeting the RNA Polymerase. Chemistry and Biodiversity 2024, 21, e202400267.

Palme, P. R.; Goddard, R.; Imming, P.; Seidel, R. W. Structural Characterization of 4-(4-Nitrophenyl)Thiomorpholine, a Precursor in Medicinal Chemistry. Molbank 2024, 2024, M1795.

Lang, M.; Ganapathy, U. S.; Mann, L.; Seidel, R. W.; Goddard, R.; Erdmann, F.; Dick, T.; Richter, A. Synthesis and in Vitro Metabolic Stability of Sterically Shielded Antimycobacterial Phenylalanine Amides. ChemMedChem 2024, 19, e202300593.

Richter, A.; Goddard, R.; Mann, L.; Siersleben, F.; Seidel, R. W. Structural Characterization of a 3-Hydroxychromone Dye Trehalose Conjugate for Fluorescent Labelling of Mycobacteria. Journal of Molecular Structure 2024, 1298, 137010.

Richter, A.; Goddard, R.; Imming, P.; Seidel, R. W. Crystal Structure and Antimycobacterial Evaluation of 2-(Cyclohexylmethyl)-7-Nitro-5-(Trifluoromethyl)- Benzo[d]Isothiazol-3(2H)-One. Acta Crystallographica , Section E: Crystallographic Communications 2023, 79, 1194–1198.

Palme, P. R.; Goddard, R.; Leutzsch, M.; Richter, A.; Imming, P.; Seidel, R. W. Structural Elucidation of the Triethylammonium Betaine of Squaric Acid. Molbank 2023, 2023, M1737.

Seidel, R. W.; Goddard, R.; Nöthling, N.; Kolev, T. M. On the Structures of Free-Base Lepidine and some Mineral Acid Salts. Journal of Molecular Structure 2023, 1285, 135460.

Pang, Y.; Nöthling, N.; Leutzsch, M.; Kang, L.; Bill, E.; van Gastel, M.; Reijerse, E.; Goddard, R.; Wagner, L.; SantaLucia, D. J.; DeBeer, S.; Neese, F.; Cornellà, J. Synthesis and Isolation of a Triplet Bismuthinidene with a Quenched Magnetic Response. Science 2023, 380, 1043–1048.

Richter, A.; Goddard, R.; Siersleben, F.; Mann, L.; Seidel, R. W. Structural Elucidation of 2-(6-(Diethylamino)Benzofuran-2-Yl)-3-Hydroxy-4H-Chromen-4-One and Labelling of Mycobacterium Aurum Cells. Molbank 2023, 2023, M1647.

Seidel, R. W.; Richter, A.; Goddard, R.; Imming, P. Synthesis, Structures, Reactivity and Medicinal Chemistry of Antitubercular Benzothiazinones. Chemical Communications 2023, 59, 4697–4715.

Lang, M.; Ganapathy, U. S.; Mann, L.; Abdelaziz, R.; Seidel, R. W.; Goddard, R.; Sequenzia, I.; Hoenke, S.; Schulze, P.; Aragaw, W. W.; Csuk, R.; Dick, T.; Richter, A. Synthesis and Characterization of Phenylalanine Amides Active against Mycobacterium Abscessus and Other Mycobacteria. Journal of Medicinal Chemistry 2023, 66, 5079–5098.

Richter, A.; Goddard, R.; Schönefeld, R.; Imming, P.; Seidel, R. W. Methyl 1-[(6-Meth­Oxy-5-Methyl­Pyrimidin-4-Yl)Meth­Yl]-1H-Benzo[d]Imidazole-7-Carboxyl­Ate: a Combined X-Ray and DFT Study. IUCRData 2023, 8, x230025.

Pang, Y.; Nöthling, N.; Leutzsch, M.; Kang, L.; Bill, E.; van Gastel, M.; Reijerse, E.; Goddard, R.; Wagner, L.; SantaLucia, D.; DeBeer, S.; Neese, F.; Cornella, J. A “Non-Magnetic” Triplet Bismuthinidene Enabled by Relativity. ChemRxiv: the Preprint Server for Chemistry 2022.

Richter, A.; Goddard, R.; Schönefeld, R.; Imming, P.; Seidel, R. W. Structural Characterization and Antimycobacterial Evaluation of a Benzimidazole Analogue of the Antituberculosis Clinical Drug Candidate TBA-7371. Acta Crystallographica Section E: Structure Reports Online 2022, 78, 1184–1188.

Kraemer, Y.; Ghiazza, C.; Ragan, A. N.; Ni, S.; Lutz, S.; Neumann, E. K.; Fettinger, J. C.; Nöthling, N.; Goddard, R.; Cornella, J.; Pitts, C. R. Strain-Release Pentafluorosulfanylation and Tetrafluoro(Aryl)Sulfanylation of [1.1.1]Propellane: Reactivity and Structural Insight. Angewandte Chemie, International Edition 2022, 61, e202211892.