Publications of Zhoutong Sun

Sun, Z.; Lonsdale, R.; Li, G.; Reetz, M. T. Comparing Different Strategies in Directed Evolution of Enzyme Stereoselectivity: Single- Versus Double-Code Saturation Mutagenesis. Chembiochem 2016, 17, 1865–1872.

Li, A.; Ilie, A.; Sun, Z.; Lonsdale, R.; Xu, J.-H.; Reetz, M. T. Whole-Cell-Catalyzed Multiple Regio- and Stereoselective Functionalizations in Cascade Reactions Enabled by Directed Evolution. Angewandte Chemie International Edition 2016, 55, 12026–12029.

Sun, Z.; Torres Salas, P.; Siirola, E.; Lonsdale, R.; Reetz, M. T. Exploring Productive Sequence Space in Directed Evolution Using Binary Patterning Versus Conventional Mutagenesis Strategies. Bioresources and Bioprocessing 2016, 3, 1–8.

Sun, Z.; Li, G.; Ilie, A.; Reetz, M. T. Exploring the Substrate Scope of Mutants Derived from the Robust Alcohol Dehydrogenase TbSADH. Tetrahedron Letters 2016, 57, 3648–3651.

Li, G.; Zhang, H.; Sun, Z.; Liu, X.; Reetz, M. T. Multiparameter Optimization in Directed Evolution: Engineering Thermostability, Enantioselectivity, and Activity of an Epoxide Hydrolase. ACS Catalysis 2016, 6, 3679–3687.

Sun, Z.; Wikmark, Y.; Backvall, J.-E.; Reetz, M. T. New Concepts for Increasing the Efficiency in Directed Evolution of Stereoselective Enzymes. Chemistry – A European Journal 2016, 22, 5046–5054.

Sun, Z.; Lonsdale, R.; Ilie, A.; Li, G.; Zhou, J.; Reetz, M. T. Catalytic Asymmetric Reduction of Difficult-to-Reduce Ketones: Triple Code Saturation Mutagenesis of an Alcohol Dehydrogenase. ACS Catalysis 2016, 6, 1598–1605.

Sun, Z.; Lonsdale, R.; Li, G.; Li, A.; Wang, J.; Reetz, M. T. Structure-Guided Triple-Code Saturation Mutagenesis: Efficient Tuning of the Stereoselectivity of an Epoxide Hydrolase. ACS Catalysis 2016, 6, 1590–1597.

Sun, Z.; Lonsdale, R.; Kong, X.-D.; Xu, J.-H.; Zhou, J.; Reetz, M. T. Reshaping an Enzyme Binding Pocket for Enhanced and Inverted Stereoselectivity: Use of Smallest Amino Acid Alphabets in Directed Evolution. Angewandte Chemie International Edition 2015, 54, 12410–12415.

Sun, Z.; Lonsdale, R.; Kong, X.-D.; Xu, J.-H.; Zhou, J.; Reetz, M. T. Reshaping an Enzyme Binding Pocket for Enhanced and Inverted Stereoselectivity: Use of Smallest Amino Acid Alphabets in Directed Evolution. Angewandte Chemie International Edition 2015, 54, 12410–12415.

Reetz, M. T.; Sun, Z.; Ilie, A. Towards the Production of Universal Blood by Structure-Guided Directed Evolution of Glycoside Hydrolases. Angewandte Chemie International Edition 2015, 54, 9158–9160.

Sun, Z.; Lonsdale, R.; Li, G.; Reetz, M. T. Developing Strategies for Engineering Efficient Biocatalysts for the Industrial Production of Chiral Compounds. Atlas of Science, another view on science. Atlas of Science: Gustavsberg March 3, 2017.