Publications of Guangyue Li

Dong, Y.; Yao, P.; Cui, Y.; Wu, Q.; Zhu, D.; Li, G.; Reetz, M. T. Manipulating the Stereoselectivity of a Thermostable Alcohol Dehydrogenase by Directed Evolution for Efficient Asymmetric Synthesis of Arylpropanols. Biological Chemistry 2019, 400, 313–321.

Li, G.; Garcia-Borràs, M.; Fürst, M. J. L. J.; Ilie, A.; Fraaije, M. W.; Houk, K. N.; Reetz, M. T. Overriding Traditional Electronic Effects in Biocatalytic Baeyer-Villiger Reactions by Directed Evolution. Journal of the American Chemical Society 2018, 140, 10464–10472.

Qu, G.; Lonsdale, R.; Yao, P.; Li, G.; Liu, B.; Reetz, M. T.; Sun, Z. Methodology Development in Directed Evolution: Exploring Options when Applying Triple-Code Saturation Mutagenesis. Chembiochem 2018, 19, 239–246.

Li, G.; Fürst, M. J. L. J.; Mansouri, H. R.; Ressmann, A. K.; Ilie, A.; Rudroff, F.; Mihovilovic, M. D.; Fraaije, M. W.; Reetz, M. T. Manipulating the Stereoselectivity of the Thermostable Baeyer–Villiger Monooxygenase TmCHMO by Directed Evolution. Organic & Biomolecular Chemistry 2017, 15, 9824–9829.

Li, G.; Maria-Solano, M. A.; Romero-Rivera, A.; Osuna, S.; Reetz, M. T. Inducing High Activity of a Thermophilic Enzyme at Ambient Temperatures by Directed Evolution. Chemical Communications 2017, 53, 9454–9457.

Li, G.; Yao, P.; Gong, R.; Li, J.; Liu, P.; Lonsdale, R.; Wu, Q.; Lin, J.; Zhu, D.; Reetz, M. T. Correction: Simultaneous Engineering of an Enzyme’s Entrance Tunnel and Active Site: the Case of Monoamine Oxidase MAO-N. Chemical Science 2017, 8, 4666–4666.

Wang, J.; Li, G.; Reetz, M. T. Enzymatic Site-Selectivity Enabled by Structure-Guided Directed Evolution. Chemical Communications 2017, 53, 3916–3928 .

Sun, Z.; Lonsdale, R.; Li, G.; Reetz, M. T. Comparing Different Strategies in Directed Evolution of Enzyme Stereoselectivity: Single- Versus Double-Code Saturation Mutagenesis. Chembiochem 2016, 17, 1865–1872.

Sun, Z.; Li, G.; Ilie, A.; Reetz, M. T. Exploring the Substrate Scope of Mutants Derived from the Robust Alcohol Dehydrogenase TbSADH. Tetrahedron Letters 2016, 57, 3648–3651.

Li, G.; Reetz, M. T. Learning Lessons from Directed Evolution of Stereoselective Enzymes. Organic Chemistry Frontiers 2016, 3, 1350–1358.

Li, G.; Zhang, H.; Sun, Z.; Liu, X.; Reetz, M. T. Multiparameter Optimization in Directed Evolution: Engineering Thermostability, Enantioselectivity, and Activity of an Epoxide Hydrolase. ACS Catalysis 2016, 6, 3679–3687.

Sun, Z.; Lonsdale, R.; Ilie, A.; Li, G.; Zhou, J.; Reetz, M. T. Catalytic Asymmetric Reduction of Difficult-to-Reduce Ketones: Triple Code Saturation Mutagenesis of an Alcohol Dehydrogenase. ACS Catalysis 2016, 6, 1598–1605.

Sun, Z.; Lonsdale, R.; Li, G.; Li, A.; Wang, J.; Reetz, M. T. Structure-Guided Triple-Code Saturation Mutagenesis: Efficient Tuning of the Stereoselectivity of an Epoxide Hydrolase. ACS Catalysis 2016, 6, 1590–1597.

Sun, Z.; Lonsdale, R.; Li, G.; Reetz, M. T. Developing Strategies for Engineering Efficient Biocatalysts for the Industrial Production of Chiral Compounds. Atlas of Science, another view on science. Atlas of Science: Gustavsberg March 3, 2017.